ROLE OF ANTI-OXIDANTS IN LIVER
Keywords:
Antioxidant activity, Reactive Oxygen Species, Free RadicalsAbstract
All living organisms utilize oxygen to metabolize and use the dietary nutrients in order to produce energy for survival. Oxygen thus is a vital component for living. Oxygen meditates chemical reactions that metabolize fats, proteins, and carbohydrates to produce energy. While oxygen is one of the most essential components for living, it is also a double-edged sword. Oxygen is a highly reactive atom that is capable of becoming part of potentially damaging molecules commonly called “Free Radicals.” Antioxidant Activity applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage. Inhibition of the reactions brought about by oxygen or peroxides. Usually, the antioxidant is effective because it can itself be more easily oxidized than the substance protected.
References
1)Halliwell B. J. Neurochem . 1995; 59:1609-23.
2)Gilbert DL, Oxygen and living processes: an inter-disciplinary approach, 1981; Springer, NY. 107-21.
3)Sandhir R and Gill KD. Hepatoprotective effects of Liv-52 on ethanol induced liver damage in rats. Ind. J. Expt. Biol. 1999; 37:762-66.
4)Berg JM, Tynaoczko JL, Stryer L. In: Biochemistry, 5 th edition, W.H. Freeman and Company, New York. 2000; 506-07.
5)Handa SS. In: Manual, TCDC International Workshop cum Training on Herbal Drugs. 1997;70-9.
6)Assimakopoulos SF, Vagianos CE, Patsoukis N, Georgiou C, Nikolopoulou V, Scopa CD. Evidence for intestinal oxidative stress in obstructive jaundice
-induced gut barrier dysfunction in rats{www.ncbi.nlm.nih.gov/pubmed/14738476}
7)Wu D, Cederbaum AI. Oxidative stress in alcoholic liver injury Oxidative stress and alcoholic liver disease.
{www.ncbi.nlm.nih.gov/pubmed/19387914].
8)Sanchez-Valle V, Chavez-Tapia NC, Uribe M, Mendez-Sanchez N. Role of oxidative stress and molecular changes in liver fibrosis: a review. {www.ncbi.nlm.nih.gov/pubmed/22709007}
9)Shah Darshan, Pharmacological Studies for investigation of hepatoprotective & antioxidant activity of extract of Balsamodendrion mukul in rats.
10)Zimmerman MD and Hayman J. Function and integrity of the liver, In: Clinical diagnosis and management by laboratory methods in: Clinical diagnosis and management by laboratory methods, 17 th Ed. 1976; 217-50.
Downloads
Published
License
Copyright (c) 2025 INTERNATIONAL JOURNAL OF PHARMACEUTICAL RESEARCH AND BIOMEDICAL ANALYSIS
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. Based on a work at www.ijprba.com
"The content of IJPRBA journal and the published Manuscripts are copy right protected. Commercial usage of the same is prohibited.
Click here for obtaining Permission for commercial use"
